mouse monoclonal anti cdc2 p34 (Santa Cruz Biotechnology)
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Santa Cruz Biotechnology
mouse monoclonal anti cdc2 p34
Mouse Monoclonal Anti Cdc2 P34, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1558 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cdc2+p34/Cdc2/pmc12887411-266-62-70
Average 96 stars, based on 1558 article reviews
Mouse Monoclonal Anti Cdc2 P34, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1558 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cdc2+p34/Cdc2/pmc12887411-266-62-70
Average 96 stars, based on 1558 article reviews
mouse monoclonal anti cdc2 p34 - by Bioz Stars,
2026-09
96/100 stars
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Immunofluorescence:Article Title: The Aurora B inhibitor ZM-447439 induces caspase-independent necrosis-like death in v-Src oncogene-expressing cells via accumulation of extra-lysosomal cathepsin B. Article Snippet: Src signaling is aberrantly activated in various cancers, and therapeutic strategies targeting Src-dependent cancers have been developed.. We previously reported that cells expressing the oncogenic mutant v-Src are resistant to microtubule-targeting agents (MTAs), yet paradoxically exhibiting sensitivity to the Aurora B inhibitor ZM-447439; however, the mechanism underlying this cytotoxicity remains unclear.. In this study, we demonstrate that the Aurora B inhibitor ZM-447439 potentiates cell death in v-Src-expressing HeLa S3 and HCT116 cells, accompanied by the accumulation of tetraploid and polyploid cells. Article Title: Identification of a novel Bax-Cdk1 signalling complex that links activation of the mitotic checkpoint to apoptosis. Article Snippet: Cells were synchronised in S-phase with thymidine (2 mM) for 24 h, washed with PBS and released into fresh medium containing 60 nM Taxol (Sigma, Poole, UK) for 0–36 h. For inhibition of Cdk1 kinase, synchronised cells that were arrested in mitosis by Taxol (60 nM for 12 h) were treated with RO3306 (Tocris Bioscience, Bristol, UK) at a concentration of 1 or 5 μM for 4 h. .. Antibodies against the following proteins were used for immunoblotting (IB), immunoprecipitation (IP) or immunofluorescence (IF): Bak (N-20, Sc1035, 1:500 for IP), Western Blot:Article Title: The Aurora B inhibitor ZM-447439 induces caspase-independent necrosis-like death in v-Src oncogene-expressing cells via accumulation of extra-lysosomal cathepsin B. Article Snippet: Src signaling is aberrantly activated in various cancers, and therapeutic strategies targeting Src-dependent cancers have been developed.. We previously reported that cells expressing the oncogenic mutant v-Src are resistant to microtubule-targeting agents (MTAs), yet paradoxically exhibiting sensitivity to the Aurora B inhibitor ZM-447439; however, the mechanism underlying this cytotoxicity remains unclear.. In this study, we demonstrate that the Aurora B inhibitor ZM-447439 potentiates cell death in v-Src-expressing HeLa S3 and HCT116 cells, accompanied by the accumulation of tetraploid and polyploid cells. Article Title: Proliferative Effect of Aqueous Extract of Sea Cucumber ( Holothuria parva ) Body Wall on Human Umbilical Cord Mesenchymal Stromal/Stem Cells Article Snippet: .. Immunoblotting was performed with β-actin (c4): sc-47778 (Santa Cruz Biotechnology, San Diego, CA, USA), Article Title: Identification of a novel Bax-Cdk1 signalling complex that links activation of the mitotic checkpoint to apoptosis. Article Snippet: Cells were synchronised in S-phase with thymidine (2 mM) for 24 h, washed with PBS and released into fresh medium containing 60 nM Taxol (Sigma, Poole, UK) for 0–36 h. For inhibition of Cdk1 kinase, synchronised cells that were arrested in mitosis by Taxol (60 nM for 12 h) were treated with RO3306 (Tocris Bioscience, Bristol, UK) at a concentration of 1 or 5 μM for 4 h. .. Antibodies against the following proteins were used for immunoblotting (IB), immunoprecipitation (IP) or immunofluorescence (IF): Bak (N-20, Sc1035, 1:500 for IP), Article Title: Proliferative effect of aqueous extract of sea cucumber (Holothuria parva) body wall on human umbilical cord mesenchymal stromal/stem cells Article Snippet: .. Immunoblotting was performed with β-actin (c4): sc-47778 (Santa Cruz Biotechnology), Flow Cytometry:Article Title: The Aurora B inhibitor ZM-447439 induces caspase-independent necrosis-like death in v-Src oncogene-expressing cells via accumulation of extra-lysosomal cathepsin B. Article Snippet: Src signaling is aberrantly activated in various cancers, and therapeutic strategies targeting Src-dependent cancers have been developed.. We previously reported that cells expressing the oncogenic mutant v-Src are resistant to microtubule-targeting agents (MTAs), yet paradoxically exhibiting sensitivity to the Aurora B inhibitor ZM-447439; however, the mechanism underlying this cytotoxicity remains unclear.. In this study, we demonstrate that the Aurora B inhibitor ZM-447439 potentiates cell death in v-Src-expressing HeLa S3 and HCT116 cells, accompanied by the accumulation of tetraploid and polyploid cells. other:Article Title: Bisphenol A exposure inhibits vascular smooth muscle cell responses: Involvement of proliferation, migration, and invasion. Article Snippet: Previous studies have associated bisphenol A (BPA) with malignant tumor formation, infertility, and atherosclerosis in vitro and in vivo.. However, the precise mechanisms through which BPA affects the cardiovascular system under normal conditions remain unclear.. Therefore, this study investigated the biological mechanisms through which BPA affects the responses of aortic vascular smooth muscle cells (VSMCs). Membrane:Article Title: PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer Article Snippet: .. Briefly, 40-50 μg of lysate was resolved by SDS-PAGE, transferred to nitrile membrane and analyzed using the following antibodies: P21 (1:1000, Abcam ab109520), phospho-CDC2 (Tyr15) (1:1500, Cell Signaling Technology 9111S), Article Title: PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer Article Snippet: .. Briefly, 40–50 μg of lysate was resolved by SDS-PAGE, transferred to nitrile membrane and analyzed using the following antibodies: P21 (1:1000, Abcam ab109520), phospho-CDC2 (Tyr15) (1:1500, Cell Signaling Technology 9111S), Immunoprecipitation:Article Title: Identification of a novel Bax-Cdk1 signalling complex that links activation of the mitotic checkpoint to apoptosis. Article Snippet: Cells were synchronised in S-phase with thymidine (2 mM) for 24 h, washed with PBS and released into fresh medium containing 60 nM Taxol (Sigma, Poole, UK) for 0–36 h. For inhibition of Cdk1 kinase, synchronised cells that were arrested in mitosis by Taxol (60 nM for 12 h) were treated with RO3306 (Tocris Bioscience, Bristol, UK) at a concentration of 1 or 5 μM for 4 h. .. Antibodies against the following proteins were used for immunoblotting (IB), immunoprecipitation (IP) or immunofluorescence (IF): Bak (N-20, Sc1035, 1:500 for IP), |
